Dr. Alexander Solonin is a distinguished molecular biologist currently serving as the Head of the Molecular Microbiology Laboratory at the Institute of Biochemistry and Physiology of Microorganisms. He earned his degree in Molecular Biology from Moscow State University in 1972, where he developed a strong foundation in biochemistry and genetic regulation. Over the years, Dr. Alexander Solonin has made pioneering contributions to understanding the mechanisms of DNA–protein recognition and the molecular regulation of bacterial toxin gene expression, particularly focusing on the Bacillus cereus hlyII gene and its interaction with the transcriptional regulator HlyIIR. His research has advanced the understanding of transcriptional control, structural determinants of DNA–protein interaction, and the molecular pathways influencing bacterial virulence, providing valuable insights for the development of novel antibacterial strategies. Dr. Alexander Solonin has authored and co-authored numerous peer-reviewed publications in high-impact international journals, contributing extensively to the fields of molecular microbiology and gene regulation. He has received several awards and honors recognizing his outstanding achievements in microbial genetics and molecular biology, reflecting his long-standing commitment to advancing scientific knowledge. In addition to his research accomplishments, Dr. Alexander Solonin serves on the editorial boards of prominent scientific journals, where he actively participates in shaping the discourse of modern molecular microbiology and mentoring emerging researchers in the field. His scientific career exemplifies a lifelong dedication to uncovering the molecular principles underlying microbial physiology and gene regulation.
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Publications
1. Kaluzhnaya, M., Khmelenina, V., Eshinimaev, B., Suzina, N., Nikitin, D., … (2001). Taxonomic characterization of new alkaliphilic and alkalitolerant methanotrophs from soda lakes of the Southeastern Transbaikal region and description of Methylomicrobium … Systematic and Applied Microbiology.
2. Baida, G., Budarina, Z. I., Kuzmin, N. P., & Solonin, A. S. (2006). Complete nucleotide sequence and molecular characterization of hemolysin II gene from Bacillus cereus. FEMS Microbiology Letters.
3. Andreeva, Z. I., Nesterenko, V. F., Yurkov, I. S., Budarina, Z. I., Sineva, E. V., … (2006). Purification and cytotoxic properties of Bacillus cereus hemolysin II. Protein Expression and Purification.
4. Andreeva, Z. I., Nesterenko, V. F., Fomkina, M. G., Ternovsky, V. I., Suzina, N. E., … (2007). The properties of Bacillus cereus hemolysin II pores depend on environmental conditions. Biochimica et Biophysica Acta (BBA) – Biomembranes.
5. Kudryashova, K. S., Chertkov, O. V., Nikitin, D. V., Pestov, N. A., Kulaeva, O. I., … (2015). Preparation of mononucleosomal templates for analysis of transcription with RNA polymerase using spFRET.