Dr. Xiaoyue Pan is an accomplished biomedical scientist and academic leader whose work centers on the molecular and physiological mechanisms of circadian rhythms and their impact on metabolic and cardiovascular diseases. Currently serving as an associate professor at an academic medical institution in the United States, Dr. Pan has built an internationally recognized research program focused on how central and peripheral circadian clocks regulate lipid metabolism, glucose transport, and vascular function. Her pioneering contributions established the essential role of core clock genes in the diurnal regulation of plasma lipids and uncovered how disruptions in these genes accelerate atherosclerosis and liver pathology. She further elucidated the role of circadian machinery in renal glucose handling during metabolic stress, advancing understanding of kidney involvement in systemic metabolic regulation. Dr. Pan’s scholarship is widely published in leading peer-reviewed journals and has attracted substantial scientific citation, reflecting the strong influence of her work within the global research community. Her research program is supported by collaborative projects spanning cardiovascular biology, metabolic disease, nephrology, and molecular physiology, and she actively contributes to scientific leadership as an editorial board member and guest editor for international journals in cardiovascular medicine. Through interdisciplinary collaboration and translational focus, her work bridges basic molecular discovery with clinically relevant disease mechanisms. Beyond research, Dr. Pan is deeply committed to academic mentorship, training the next generation of scientists in rigorous experimental design and integrative biological thinking. The societal impact of her work lies in its relevance to prevalent chronic diseases, including atherosclerosis, liver steatosis, kidney disease, and neurodegenerative disorders, offering novel mechanistic insights that may guide future preventive and therapeutic strategies. Her sustained contributions position her as a respected authority in circadian biology and metabolic disease research on a global scale. He has 2342 citations from 45 documents with an h-index of 27.
Profiles: Google Scholar | Scopus | ORCID
Publications
1. Pan, X., & Hussain, M. M. (2009). Clock is important for food and circadian regulation of macronutrient absorption in mice. Journal of Lipid Research.
2. Pan, X., Zhang, Y., Wang, L., & Hussain, M. M. (2010). Diurnal regulation of MTP and plasma triglyceride by CLOCK is mediated by SHP. Cell Metabolism.
3. Pan, X., Jiang, X. C., & Hussain, M. M. (2013). Impaired cholesterol metabolism and enhanced atherosclerosis in clock mutant mice. Circulation.
4. Pan, X., & Hussain, M. M. (2007). Diurnal regulation of microsomal triglyceride transfer protein and plasma lipid levels. Journal of Biological Chemistry.
5. Pan, X., & Hussain, M. M. (2012). Gut triglyceride production. Biochimica et Biophysica Acta (BBA) – Molecular and Cell Biology of Lipids.