Luigi Montano | Environmental Health | Research Excellence Award

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Dr. Luigi Montano | Environmental Health | Research Excellence Award

Senior Consultant | Azienda Sanitaria Locale Salerno | Itly

Luigi Montano, MD, PhD, is a physician–scientist specializing in urology and andrology, with advanced expertise in reproductive health, environmental pathology, lifestyle medicine, and evolutionary biology. His research focuses on the interactions between environment, nutrition, lifestyle, and male fertility, with particular attention to emerging risk factors such as pollutants, microplastics, and dietary patterns. He has led and coordinated several interdisciplinary research initiatives integrating clinical medicine, public health, and environmental sciences, fostering national and international collaborations across Europe and beyond. His scholarly work includes peer-reviewed publications widely cited in the fields of andrology, reproductive biology, and environmental health. Beyond academia, his work has contributed to public health awareness, prevention strategies, and policy dialogue on fertility preservation, sustainability, and healthy lifestyles, reinforcing the societal relevance of translational and prevention-oriented medical research. He has 2232 citations from 71 documents with an h-index of 24.

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Paola Vasquez | Public Health | Research Excellence Award

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Mrs. Paola Vasquez | Public Health | Research Excellence Award

Senior Research | Murdoch University | Australia

Paola Vásquez is a registered nurse and midwife with advanced expertise in public health, health management, and health technology assessment. Her work spans community health, policy implementation, academic leadership, and applied research, with a strong focus on health equity, rare diseases, Indigenous health, and patient and public involvement. She is a Senior Research Fellow at Murdoch University’s Ngangk Yira Institute for Change, leading community-centred research that supports intergenerational wellbeing for First Nations families. Her scholarly contributions include peer-reviewed publications in high-impact international journals, systematic reviews, and policy-relevant economic and social preference analyses. She collaborates extensively with academic, governmental, and international organisations across Australia, Latin America, and Europe. Her work has directly informed national health policy, pharmaceutical funding decisions, and culturally responsive models of care, generating meaningful societal impact through evidence-based decision-making and inclusive research practice. She has 35 citations from 5 documents with an h-index of 4.

Citation Metrics (Scopus)

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                       🟦 Citations             🟥 Documents          🟩 h-index

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Sajida Batool | Public Health | Excellence in Research Award

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Assoc. Prof. Dr. Sajida Batool | Public Health | Excellence in Research Award

Associate Professor | University of Sargodha | Pakistan

Dr. Sajida Batool is a distinguished scholar in zoology and reproductive physiology whose work spans molecular toxicology, environmental health, and endocrine disruption, with a strong focus on understanding how chemical exposures influence reproductive and systemic physiology in both animal models and human health–relevant contexts. Her academic training, international research exposure, and extensive laboratory expertise in advanced techniques such as immunohistochemistry, histology, genotoxicity assays, and molecular diagnostics have enabled her to contribute impactful evidence within the fields of toxicological pathology, reproductive biology, and environmental risk assessment. She has authored a substantial portfolio of peer-reviewed publications in reputable international journals, reflecting a sustained record of scientific productivity, interdisciplinary collaborations, and contributions to global knowledge on chemical toxicants including heavy metals, endocrine-disrupting compounds, industrial pollutants, and plant-based therapeutic agents. Her research collaborations extend across multidisciplinary teams working in molecular biology, environmental sciences, pharmacology, and wildlife genetics, underscoring her role in bridging classical zoology with emerging biomedical and ecological sciences. Through her work on oxidative stress, DNA integrity, immunomodulation, reproductive toxicology, and phytochemical interventions, she has advanced insights with direct implications for public health, environmental safety, and evidence-based therapeutic development. She has also played a meaningful role in academic capacity building by organizing specialized workshops on reference management, research ethics, and statistical computing, fostering professional development within the scientific community. Her contributions have shaped scientific understanding, supported translational research, and provided foundational evidence guiding safer environmental practices and potential biological remedies for toxin-induced damage, establishing her as a dedicated health-science–aligned researcher with significant societal and academic impact. She has 201 citations from 29 documents with an h-index of 8.

Profiles: Google Scholar | Scopus | ORCID

Featured Publications

1. Akram, Z., Jalali, S., Shami, S. A., Ahmad, L., Batool, S., & Kalsoom, O. (2010). Adverse effects of arsenic exposure on uterine function and structure in female rat. Experimental and Toxicologic Pathology.

2. Ahmad, L., Jalali, S., Shami, S. A., Akram, Z., Batool, S., & Kalsoom, O. (2010). Effects of cryopreservation on sperm DNA integrity in normospermic and four categories of infertile males. Systems Biology in Reproductive Medicine.

3. Akram, Z., Jalali, S., Shami, S. A., Ahmad, L., Batool, S., & Kalsoom, O. (2009). Genotoxicity of sodium arsenite and DNA fragmentation in ovarian cells of rat. Toxicology Letters.

4. Batool, S., Batool, S., Shameem, S., Batool, T., & Batool, S. (2022). Effects of dibutyl phthalate and di(2-ethylhexyl) phthalate on hepatic structure and function of adult male mice. Toxicology and Industrial Health.

5. Akhtar, M. T., Almas, T., Safdar, S., Saadia, M., Qadir, R., Batool, S., Mustaqeem, M., … (2023). Antioxidant, hypoglycemic, antilipidemic, and protective effect of polyherbal emulsion (F6-Smonsecce) on alloxan-induced diabetic rats. ACS Omega.

Feiying he | Public Health | Research Excellence Award

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Ms. Feiying he | Public Health | Research Excellence Award

Associate Professor | Southern Medical University | China

The scholar is an associate professor in public health policy and management at Southern Medical University with interdisciplinary training spanning health management, management science, and public health policy from Guangzhou University of Traditional Chinese Medicine, Sun Yat-sen University, and Southern Medical University, and has established a strong academic profile at the intersection of mind–body medicine, health behavior, intelligent health management, aging health, and mind–brain comorbidity modeling supported by artificial intelligence. The researcher has led and participated in multiple competitive national, provincial, and industry-funded projects focusing on comorbidity risk prediction, community-based intelligent elderly care, intestinal microecology and health, primary medical service optimization, and integrated healthcare for active aging. Scholarly outputs include peer-reviewed publications in leading domestic and international journals such as BMC Health Services Research and Chinese General Practice, with influential studies on health literacy segmentation, smart home health applications, physician professional behavior, ethical practice, turnover intention, and the psychosocial determinants of diabetes–depression comorbidity. As editor-in-chief and associate editor of several academic monographs on elderly health risk management, clinical geriatrics, intelligent healthcare, and entrepreneurship management, the scholar has made sustained contributions to academic capacity building and applied education. Professional service includes leadership and editorial roles in multiple provincial and national academic associations related to psychosomatic medicine, psychiatry, and medical–industry integration. Through sustained university–industry collaboration and translational research, the scholar’s work has informed community health service optimization, promoted intelligent elderly care models, and strengthened evidence-based strategies for chronic disease comorbidity management, generating meaningful public health, technological, and societal impact at regional and national levels. She has 88 citations from 13 documents with an h-index of 4.

Profile: Scopus 

Featured Publications

  1. Revisiting successful aging through a machine learning approach to quantifying the influence of chronic diseases. (2025). Scientific Reports

 

Saeed Aghebat Bekheir | Translational Research | Research Excellence Award

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Dr. Saeed Aghebat Bekheir | Mental Health | Research Excellence Award

PhD Candidate in Toxicology | Tehran University of Medical Sciences | Iran

Dr. Saeed Aghebat Bekheir is a dedicated researcher and PhD candidate in Toxicology at Tehran University of Medical Sciences, working under the mentorship of Prof. Abdollahi. His research focuses on mitochondrial toxicology, cardiotoxicity, and mechanistic modeling of toxin-induced bioenergetic failure, with a particular emphasis on developing therapeutic strategies for aluminum phosphide–induced mitochondrial dysfunction. Dr. Aghebat Bekheir has demonstrated expertise in a wide range of experimental approaches, including in vivo animal studies, cellular and molecular assays, and in vitro toxicological models, integrating mechanistic toxicology with translational research to address acute mitochondrial injury and cardiotoxicity. His scholarly contributions are reflected in several peer-reviewed publications in high-impact journals, and he actively serves as a reviewer for multiple journals in toxicology and biomedical sciences, highlighting his commitment to advancing scientific rigor and dissemination. Collaboratively, he engages in research partnerships within the toxicology and mitochondrial research community, fostering interdisciplinary approaches to environmental and translational toxicology challenges. His work contributes to a deeper understanding of oxidative stress, bioenergetic disturbances, and cardiotoxic mechanisms, with broader implications for public health and therapeutic innovation. Beyond his laboratory and scholarly pursuits, Dr. Aghebat Bekheir’s research emphasizes societal relevance by addressing environmental toxicants and their impacts on human health, providing foundational knowledge for developing interventions to mitigate toxicity-related diseases. Through his professional memberships, editorial activities, and collaborative initiatives, he actively contributes to shaping the global toxicology landscape, promoting evidence-based strategies, and inspiring emerging researchers in the field. His ongoing research underscores a commitment to integrating scientific excellence with practical solutions for human health, reflecting both scholarly distinction and societal impact. He has 23 citations from 5 documents with an h-index of 3.

Profiles: Google Scholar | Scopus

Featured Publications

1. Ghanati, K., Jahanbakhsh, M., Shakoori, A., Aghebat-Bekheir, S., … (2024). The association between polycystic ovary syndrome and environmental pollutants based on animal and human study; a systematic review.

2. Ghanati, K., Eghbaljoo, H., Akbari, N., Mazaheri, Y., Aghebat-Bekheir, S., … (2023). Determination of melamine contamination in milk with various packaging: A risk assessment study.

3. Aghebat-Bekheir, S., Abdollahi, M. (2024). Discovering the most impactful treatments for aluminum phosphide cardiotoxicity gleaned from systematic review of animal studies.

4. Reihani, A., Marboutian, F., Aghebat-Bekheir, S., Reyhani, A., Akhgari, M. (2024). Diagnostic aspects of paraquat in the forensic toxicology: A systematic review.

5. Aghebat-Bekheir, S., Hekmatirad, S., Asar, N., Abdollahi, M. (n.d.). Aluminum phosphide as a model for exploring acute mitochondrial disorders.

Marta Kisiel | Occupational Health | Research Excellence Award

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Dr. Marta Kisiel | Occupational Health | Research Excellence Award 

Associate Professor | Uppsala University | Sweden

Marta A. Kisiel is a specialist physician and Associate Professor in Occupational and Environmental Medicine at Uppsala University and Uppsala University Hospital, with an interdisciplinary background spanning medicine, polymer chemistry, and environmental health sciences. Her academic profile is distinguished by a strong integration of clinical practice and translational research, with a primary focus on the health effects of environmental and occupational exposures, post-viral conditions, work capacity, quality of life, respiratory function, and biological markers of disease. She has led and contributed to major research initiatives on post-COVID conditions and socioeconomic inequalities in environmental health risks, supported by competitive national foundations and regional research councils. Her publication record reflects sustained productivity in high-quality peer-reviewed journals with consistent citation impact, demonstrating both scientific rigor and international visibility. Dr. Kisiel maintains active collaborations with multidisciplinary teams across Sweden and internationally, including partnerships in clinical medicine, public health, and preventive psychiatry, and she has been instrumental in establishing cross-specialty clinical forums that bridge pulmonology, dermatology, and occupational medicine. As a principal investigator and supervisor, she plays a central role in training doctoral candidates and mentoring early-career clinicians and researchers, while also contributing extensively to undergraduate and specialist medical education through course leadership, thesis supervision, and problem-based learning. Beyond academia, she serves as an expert advisor to regional health authorities on evidence-based care for post-COVID conditions, contributes to national clinical knowledge platforms, and regularly acts as peer reviewer and committee member within the scientific community. Through her combined research, teaching, clinical leadership, and policy advisory work, Dr. Kisiel has achieved significant societal impact by strengthening occupational health practice, informing public health decision-making, and advancing care for individuals affected by environmentally and work-related diseases.  She has 824 citations from 51 documents with an h-index of 16.

Profiles: Google Scholar | Scopus | ORCID

Featured Publications

1. Thambamroong, T., Seetalarom, K., Saichaemchan, S., Pumsutas, Y., & colleagues. (2022). Efficacy of curcumin on treating cancer anorexia-cachexia syndrome in locally or advanced head and neck cancer: A double-blind, placebo-controlled randomised phase IIa trial.

2. Chirapongsathorn, S., Rintaravitoon, W., Tangjaturonrasme, B., & colleagues. (2025). Effect of a ketogenic diet on metabolic dysfunction-associated steatotic liver disease (MASLD) progression: A randomized controlled trial.

3. Chirapongsathorn, S., Rintaravitoon, W., Tangjaturonrasme, B., & colleagues. (2023). Effect of a ketogenic diet on nonalcoholic fatty liver disease (NAFLD) progression: A randomized controlled trial.

4. Thambamroong, T., Seetalarom, K., Saichaemchan, S., Pumsutas, Y., & colleagues. (2022). Efficacy of curcumin on treating cancer anorexia-cachexia syndrome in locally or advanced head and neck cancer: A double-blind, placebo-controlled randomised trial.

5. Satirapoj, B., Varothai, N., Boonyagarn, N., Pumsutas, Y., Chotsriluecha, S., & colleagues. (2020). Effect of renal specific oral nutrition (ONCE Renal) on dietary intake and serum electrolytes in chronic kidney disease stage IV.

Naseem Akhtar | Environmental Health | Editorial Board Member

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Dr. Naseem Akhtar | Environmental Health | Editorial Board Member

Postdoctoral Fellow | Universiti Sains Malaysia | Malaysia

Naseem Akhtar is a dedicated PhD researcher in the School of Industrial Technology at the Department of Environmental Technology, Universiti Sains Malaysia, whose scholarly work advances critical understanding of hydrology, hydrogeology, and environmental science with particular attention to water quality, groundwater dynamics, and pollution assessment in vulnerable landscapes. His research portfolio reflects a strong commitment to addressing the complex interactions among natural processes, anthropogenic pressures, and hydrogeochemical transformations that influence freshwater sustainability. Through influential publications in reputable international journals, he has contributed to major domains such as water quality index refinement using decision-support methodologies, multivariate analysis of heavy metals in groundwater systems, hydrogeochemical characterization for drinking and irrigation suitability, and the identification of pollution hotspots within rapidly urbanizing watersheds. His collaborative engagements span multidisciplinary teams across environmental technology, analytical chemistry, public health, and sustainable agriculture, demonstrating a capacity to integrate scientific rigour with applied relevance. He has co-authored impactful studies that inform groundwater management strategies, highlight the risks associated with heavy metal contamination, and propose improved frameworks for monitoring and decision-making in water-stressed regions. His contributions also extend to cross-sectoral research involving sustainability modelling and early disease detection programs, underscoring the broader societal relevance of his work. With an expanding citation record and a growing body of scholarly outputs, he continues to shape contemporary discourse on environmental resilience, resource management, and hydrological sustainability. His research trajectory positions him as an emerging scholar committed to producing evidence-based solutions that address global water challenges and support long-term environmental stewardship. He has 1253 citations from 21 documents with an h-index of 7.

Profiles: Google Scholar | Scopus | ORCID

Featured Publications

1. Akhtar, N., Ishak, M. I. S., Bhawani, S. A., & Umar, K. (2021). Various natural and anthropogenic factors responsible for water quality degradation: A review.

2. Akhtar, N., Ishak, M. I. S., Ahmad, M. I., Umar, K., Md Yusuff, M. S., Anees, M. T., … (2021). Modification of the water quality index (WQI) process for simple calculation using the multi-criteria decision-making (MCDM) method: A review.

3. Akhtar, N., Syakir, M. I., Rai, S. P., Saini, R., Pant, N., Anees, M. T., Qadir, A., & Khan, U. (2020). Multivariate investigation of heavy metals in groundwater for irrigation and drinking in Garautha Tehsil, Jhansi District, India.

4. Ahmed, S., Akhtar, N., Rahman, A., Mondal, N. C., Khurshid, S., Sarah, S., … (2022). Evaluating groundwater pollution with emphasis on heavy metal hotspots in an urbanized alluvium watershed of Yamuna River, northern India.

5. Akhtar, N., Syakir, M. I., Anees, M. T., Qadir, A., & Yusuff, M. S. (n.d.). Characteristics and assessment of groundwater.

Rastegar Hoseini | Public Health | Best Researcher Award

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Assist. Prof. Dr. Rastegar Hoseini | Public Health | Best Researcher Award 

 Physiology | Razi University | Iran

Dr. Rastegar Hosseini is an accomplished academic and researcher in the field of Sport Physiology, with a specialized focus on Sports Nutrition. Serving as a faculty member at the Faculty of Sport Sciences, Razi University, Kermanshah, he has established a strong reputation for his work at the intersection of nutrition, exercise physiology, and athletic performance. His scholarly contributions reflect a commitment to advancing knowledge in exercise metabolism, dietary strategies, and physiological adaptations to training. Through extensive peer-reviewed publications in internationally indexed journals, Dr. Hosseini has contributed significantly to understanding the complex biochemical and nutritional determinants of performance and recovery in athletes. His research emphasizes the translation of laboratory findings into evidence-based nutritional protocols that enhance performance outcomes, promote metabolic health, and support sustainable athletic development. In addition to his academic output, he has been actively involved in national collaborations with sports federations, wellness centers, and interdisciplinary health networks, where his expertise has informed training methodologies and dietary planning. As a mentor and educator, Dr. Hosseini continues to guide postgraduate research projects that explore innovative nutritional interventions and metabolic adaptations in sport and exercise science. His work embodies a balanced integration of scientific rigor, practical application, and educational leadership, contributing meaningfully to both the academic community and the broader field of applied sports science. Through his collaborations with research groups across Iranian universities and active participation in national health and performance initiatives, he has reinforced the importance of science-driven approaches in optimizing human performance and well-being. Dr. Hosseini’s professional affiliations with leading sport physiology and nutrition societies further underscore his dedication to research excellence, academic integrity, and the advancement of knowledge that benefits both elite athletes and the general population through improved understanding of nutrition and exercise physiology. He has 417 citations from 52 documents with an h-index of 12.

Profiles: Google Scholar | Scopus | ORCID

Featured Publications

1. Vitamin D and exercise improve VEGF-B production and IGF-1 levels in diabetic rats: Insights into the role of miR-1 suppression. (2025).

2. The role of the SIRT1 and mTOR pathways in exercise-induced β-cell senescence reduction in type 2 diabetes mellitus. (2025).

3. Kynurenine pathway modulation by exercise in multiple sclerosis: Implications for neuroprotection and inflammation. (2025).

4. Combined effects of sodium alginate supplementation with HIIT and MICT on CCK and PYY levels in men with metabolic syndrome. (2025). 

5. Demographic, cultural, and health correlates of physical activity and sports participation among adults in Kermanshah province, Iran. (2025).

Duo Liu | Epidemiology | Best Researcher Award

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Prof. Duo Liu | Epidemiology | Best Researcher Award 

Deputy Director, Department of Clinical Pharmacy | Harbin Medical University | China

Professor Duo Liu, Chief Pharmacist and Doctoral Supervisor at Harbin Medical University Cancer Hospital, is a distinguished pharmaceutical scientist whose research has significantly advanced the fields of pharmacogenomics, pharmacoepidemiology, and precision oncology. With a strong background in medical genetics and pharmacology, Professor Liu has developed a research portfolio that bridges molecular pharmacology with clinical translation, focusing on the genetic mechanisms underlying cancer susceptibility, therapeutic response, and drug resistance. His pioneering contributions include transcriptome-wide association studies identifying novel genetic determinants of pancreatic and prostate cancer risk, as well as investigations into the role of NADPH oxidase polymorphisms and oxidative stress in tumor biology and treatment outcomes. Professor Liu’s scholarly work, published in leading international journals such as Cancer Research, Carcinogenesis, and International Journal of Cancer, has garnered wide recognition for its methodological rigor and clinical relevance. He has successfully led multiple national and institutional research grants, including projects supported by the National Natural Science Foundation of China, and has been honored with several prestigious distinctions for excellence in pharmaceutical sciences and young investigator achievements. As an active member of numerous professional societies, including the Chinese Pharmacological Society and the Anti-Cancer Association of China, Professor Liu contributes to shaping the evolving landscape of cancer pharmacotherapy and drug epidemiology. His collaborations with global research institutions, notably the University of Hawaii Cancer Center, underscore his commitment to advancing international scientific exchange and translational medicine. Through his leadership in clinical pharmacy and mentorship of emerging scientists, Professor Liu continues to drive innovation in personalized cancer treatment and rational drug use, promoting evidence-based healthcare practices that enhance patient outcomes and public health impact worldwide.

Profile: ORCID 

Featured Publications

1. Chen, C., Dong, Q., Wang, H., Dong, S., Wang, S., Lin, W., Jia, C., Dong, M., Jin, Y., & Liu, D. (2025, January 8). The association between NADPH oxidase (NOX) polymorphisms with immunohistochemistry and survival in diffuse large B cell lymphoma patients. Annals of Hematology.

2. Wang, S. F., Dong, S. Q., Dong, Q., Lin, W. X., Dong, M., & Liu, D. (2024). Natural product-induced oxidative stress-synergistic anti-tumor effects of chemotherapeutic agents. Traditional Medicine Research.

3. Dong, S., Chen, C., Di, C., Wang, S., Dong, Q., Lin, W., & Liu, D. (2024, December). The association between NADPH oxidase 2 (NOX2) and drug resistance in cancer. Current Cancer Drug Targets.

4. Liu, D., Bae, Y. E., Zhu, J., Zhang, Z., Sun, Y., Deng, Y., Wu, C., & Wu, L. (2023, December 15). Splicing transcriptome-wide association study to identify splicing events for pancreatic cancer risk. Carcinogenesis.

5. Liu, D., Zhao, T., Zhu, J., Sharapov, S., Tiys, E., & Wu, L. (2023, December 4). Associations between genetically predicted plasma N-glycans and pancreatic cancer risk. All Life.

Zaira Ahmad | Environmental Health | Best Researcher Award

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Dr. Zaira Ahmad | Environmental Health | Best Researcher Award 

Assistant Professor | Lahore College for Women University | Pakistan

Dr. Zahra Molazem is a distinguished academic and healthcare researcher currently serving as an Associate Professor at Shiraz University of Medical Sciences, Iran. She earned her Ph.D. in Nursing Education from the same institution, where she also completed her M.Sc. and B.Sc. in Nursing. Dr. Molazem’s research primarily focuses on patient-centered care, digital health innovations, psychosocial support, and nursing education reform, with a special emphasis on cardiovascular and oncology patient management. Her scholarly contributions include notable 2025 studies such as the evaluation of smartphone-based self-help interventions for patients with acute coronary syndrome and the clinical application of Citrus aurantium aromatherapy to reduce chemotherapy-induced nausea and vomiting in breast cancer patients. She has also published influential qualitative research on caregiving burdens, patient handoffs, and family-centered care models, widely recognized for advancing evidence-based practice and holistic healthcare. Dr. Molazem has received several institutional awards for research excellence and innovation in nursing education and has actively participated in national and international conferences promoting interdisciplinary collaboration in healthcare. Beyond her research, she serves on editorial boards and peer-review panels for several reputable scientific journals in nursing and clinical health sciences, contributing to the global dissemination of best practices in patient care and digital health integration. Through her academic leadership and commitment to compassionate, evidence-driven practice, Dr. Zahra Molazem continues to shape the evolving landscape of modern healthcare education and clinical research. She has 121 citations from 11 documents with an h-index of 4.

Profiles: Google Scholar | Scopus | ORCID

Featured Publications

1. Khawar, M. B., Abbasi, M. H., Hussain, S., Riaz, M., Rafiq, M., Mehmood, R., et al. (2021). Psychological impacts of COVID-19 and satisfaction from online classes: Disturbance in daily routine and prevalence of depression, stress, and anxiety among students of Pakistan.

2. Fahim, S., Nisar, N., Ahmad, Z., Asghar, Z., Said, A., Atif, S., Ghani, N., Qureshi, N., et al. (2019). Managing paper and pulp industry by-product waste utilizing sludge as a bio-fertilizer.

3. Nisar, N., Mehmood, S., Nisar, H., Jamil, S., Ahmad, Z., Ghani, N., Oladipo, A. A., et al. (2018). Brassicaceae family oil methyl esters blended with ultra-low sulphur diesel fuel (ULSD): Comparison of fuel properties with fuel standards.

4. Abbasi, A. M., David, K., Idnan, M., Ahmad, Z., & Qureshi, R. (2018). Effect of time-lapse administration of Panadol (Paracetamol) on spleen and kidney functions of adult albino mice. RADS Journal of Biological Research & Applied Sciences.

5. Khawar, T. M. B., Fatima, N., Abbasi, M. H., Sheikh, N., & Amaan, A. N. (Year not specified). Role and molecular mechanisms of lysosomes and cathepsins in neuropathology and aging: New insights.