Juheli Sadhukhan | Public Health | Best Researcher Award

Ms. Juheli Sadhukhan | Public Health | Best Researcher Award

Research Scholar at University of Calcutta, India

Juheli Sadhukhan, currently a Senior Research Fellow at the University of Calcutta, stands out as a promising candidate for the Best Researcher Award due to her impactful contributions to health-focused chemical research. With a strong academic foundation, including GATE and CSIR-NET qualifications (AIR 27), her work emphasizes the synthesis of novel heterocyclic compounds for anticancer and antileishmanial applications. She has published six research papers in reputed journals and earned international recognition, including the RSC Best Poster Award at ICCHD-2025. Her research also includes the development of fluorescent probes for selective metal ion detection and live-cell imaging. Though still early in her career, her dedication to scientific advancement, active participation in academic events, and RSC membership demonstrate a commitment to growth and excellence. Enhancing citation impact, engaging in international collaborations, and pursuing patents or industry ties could further elevate her profile. Overall, she exemplifies a dedicated and innovative researcher deserving of recognition.

Professional Profile

Scopus Profile | ORCID Profile

Education

Juheli Sadhukhan has built a strong academic foundation rooted in prestigious Indian institutions. She pursued her education at the University of Calcutta and NIT Durgapur, both renowned for their academic rigor and research emphasis. Demonstrating academic excellence early in her career, she qualified for both GATE 2020 and CSIR-NET 2020, securing an impressive All India Rank (AIR) of 27 in the latter—an achievement that highlights her deep understanding of chemical sciences. Her academic journey has been complemented by consistent participation in specialized training programs and workshops, including hands-on experience in single-crystal X-ray diffraction, which has enriched her technical skillset. Juheli’s educational background is not only marked by strong theoretical knowledge but also by a proactive approach to applying this knowledge through research. Her formal education has provided her with the critical thinking, problem-solving, and analytical capabilities necessary to engage in complex interdisciplinary research, particularly in drug development and molecular diagnostics.

Experience

Juheli Sadhukhan’s professional experience as a Senior Research Fellow at the University of Calcutta reflects her deep engagement in interdisciplinary scientific research, particularly in the fields of medicinal and organic chemistry. Her ongoing work involves the design and synthesis of novel heterocyclic compounds aimed at developing effective anticancer and antileishmanial drugs, contributing directly to solutions for pressing global health challenges. She has also worked on developing fluorescent probes for metal ion detection and endogenous H₂S sensing, demonstrating expertise in both experimental and computational approaches. Juheli has presented her research at national and international conferences, including ICCHD-2025, where she earned the RSC Best Poster Award. Her hands-on involvement in laboratory work, combined with participation in advanced workshops such as single-crystal X-ray diffraction, underscores her technical proficiency and research versatility. Her experience is further enhanced by RSC membership, which keeps her connected to global developments in chemical sciences and strengthens her collaborative potential.

Research Interest

Juheli Sadhukhan’s research interests lie at the intersection of organic synthesis, medicinal chemistry, and molecular diagnostics, with a strong focus on addressing critical health challenges such as cancer and leishmaniasis. Her primary area of investigation involves the design and synthesis of novel heterocyclic compounds to evaluate their anticancer and antileishmanial properties, aiming to contribute to the development of more effective and targeted therapeutics. She is particularly interested in the structure–activity relationship (SAR) of small molecules and their interactions with biological targets. In addition to therapeutic research, she explores the development of fluorescent probes for the selective and sensitive detection of biologically relevant species such as metal ions (e.g., Pd²⁺, Hg²⁺) and endogenous hydrogen sulfide (H₂S), incorporating live-cell imaging techniques. Her interdisciplinary approach blends spectroscopic analysis, computational modeling, and cellular biology, offering a comprehensive platform for both diagnostic innovation and drug discovery in modern health science.

Award and Honor

Juheli Sadhukhan has earned notable recognition for her academic and research excellence through various awards and honors. One of her most distinguished achievements is receiving the Royal Society of Chemistry (RSC) Best Poster Award at the prestigious International Conference on Chemistry for Health, Development and Environment (ICCHD-2025), which highlighted the novelty and impact of her research on drug discovery and diagnostics. Her academic merit is further demonstrated by her success in highly competitive national-level examinations, including qualifying for GATE 2020 and the CSIR-NET 2020 with an outstanding All India Rank (AIR) of 27, placing her among the top emerging scholars in chemical sciences. These accomplishments reflect her dedication, innovation, and ability to conduct research that meets international standards. Participation in various academic conferences, workshops, and technical training programs also exemplifies her ongoing commitment to academic excellence and scientific growth, reinforcing her position as a rising talent in the research community.

Research Skill

Juheli Sadhukhan possesses a diverse and well-rounded set of research skills that span across synthetic organic chemistry, analytical techniques, and biomedical applications. She has expertise in the design and synthesis of heterocyclic compounds, with a focus on their biological evaluation for anticancer and antileishmanial activities. Her hands-on proficiency in spectroscopic methods—such as NMR, UV-Vis, and fluorescence spectroscopy—supports her ability to characterize complex molecular structures and probe biological interactions. Juheli is also skilled in live-cell imaging techniques and the development of fluorescent sensors for detecting biologically relevant ions like Pd²⁺ and Hg²⁺. In addition, she integrates computational modeling into her workflow to predict molecular behavior and optimize drug-target interactions. Her experience extends to working with protein-binding studies, particularly using serum albumin, and DNA-binding assays for GC-rich regions. These technical competencies, coupled with a keen analytical mindset, make her an adept and versatile researcher in modern chemical biology and health science.

Publications Top Notes

  • Title: Recognition of GC base pairs of B-DNA by coumarin-based benzimidazopyrimidines
    Authors: Juheli Sadhukhan, Pabitra Mandal, Smritimoy Pramanik, Subhajit Guria, Alomgir Shah Kabir, Debojyoti Das, Susanta Sekhar Adhikari
    Year: 2025
    Citation: DOI: 10.1039/D4OB02055C

  • Title: A Novel Quinoline‐Based Turn‐On Fluorescent Probe for Rapid Sensing of Endogenous H₂S at the Intracellular Level
    Authors: Tanushree Mishra, Subhajit Guria, Juheli Sadhukhan, Debojyoti Das, Alomgir Shah Kabir, Subhajit Ghosh, Susanta Sekhar Adhikari
    Year: 2025
    Citation: DOI: 10.1002/slct.202502099

  • Title: Naphthalimide‐Triazole Affixed Rhodamine Probe for FRET‐Based Selective Detection of Pd²⁺ Ion in Living Cells
    Authors: Subhajit Guria, Alomgir Shah Kabir, Juheli Sadhukhan, Somnath Khanra, Debasis Das, Susanta Adhikari
    Year: 2025
    Citation: DOI: 10.1002/ajoc.202500082

  • Title: Synthesis of Novel Coumarin-Appended Dihydrothiopyrimidinones and Evaluation of Their Binding Interactions with Bovine Serum Albumin
    Authors: Susanta Sekhar Adhikari, Debojyoti Das, Juheli Sadhukhan, Pabitra Mandal, Smritimoy Pramanik, Alomgir Shah Kabir
    Year: 2025
    Citation: DOI: 10.1055/s-0043-1775488

  • Title: Fluorometric detection of a chemical warfare agent mimic (DCP) using a simple hydroxybenzothiazole–diaminomaleonitrile based chemodosimeter
    Authors: Manas Kumar Das, Tanushree Mishra, Subhajit Guria, Debojyoti Das, Juheli Sadhukhan, Sushmita Sarker, Koushik Dutta, Arghya Adhikary, Dipankar Chattopadhyay, Susanta Sekhar Adhikari
    Year: 2023
    Citation: DOI: 10.1039/D2NJ04260F

  • Title: Small-Molecule Probe for Sensing Serum Albumin with Consequential Self-Assembly as a Fluorescent Organic Nanoparticle for Bioimaging and Drug-Delivery Applications
    Authors: Subhajit Guria, Avijit Ghosh, Priyanka Upadhyay, Manas Kumar Das, Tanushree Mishra, Arghya Adhikary, Susanta Adhikari
    Year: 2020
    Citation: DOI: 10.1021/acsabm.0c00146

Conclusion

Juheli Sadhukhan exemplifies the qualities of a dedicated and emerging research professional whose innovative work in health-related chemical sciences contributes meaningfully to diagnostic and therapeutic development. Her solid academic background, notable conference recognition, and focused publication record establish her as a rising talent in biomedical research. While there remains room to strengthen her research visibility and leadership footprint, her current achievements and potential trajectory strongly support her nomination for the Best Researcher Award, recognizing her as a dynamic force driving innovation at the intersection of chemistry and health science.