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Dr. Minzhao Lin | Biomedical Engineering | Best Researcher Award

Lecturer at Dezhou University, China

Minzhao Lin, a Lecturer at Dezhou College and Ph.D. candidate in Biology and Medicine at Sun Yat-sen University, stands out as a highly promising candidate for the Best Researcher Award. His research focuses on ultrasound-based drug delivery, nanomedicine, and cancer immunotherapy—fields at the cutting edge of biomedical innovation. With over 24 peer-reviewed publications, including articles in Nature Communications, Biomaterials, and Advanced Science, Lin has made significant contributions to targeted therapies and tumor microenvironment modulation. He demonstrates technical mastery in nanocarrier design, molecular biology, and in vivo cancer models, supported by active roles in national key research projects and lab management. His interdisciplinary approach and early leadership in project coordination highlight both academic excellence and practical impact. While he could benefit from increased international exposure and independent research initiatives, his achievements clearly mark him as an outstanding young scientist, making him a strong contender for this prestigious recognition.

Professional Profile

Education🎓

Minzhao Lin has pursued a well-rounded and progressive academic journey that reflects his commitment to interdisciplinary scientific excellence. He is currently completing his Ph.D. in Biology and Medicine at Sun Yat-sen University (2020–2024), where his research focuses on nanomedicine, cancer immunotherapy, and ultrasound-responsive drug delivery systems. Prior to this, he earned a Master’s degree in Plant Prevention and Biomaterials from South China Agricultural University (2017–2020), deepening his expertise in biofunctional materials and environmental interactions. His academic foundation was laid with a Bachelor’s degree in Environmental Science from the same university (2013–2017), where he graduated with a high GPA of 4.15/5 and ranked 5th out of 330 students, a testament to his early academic excellence. Lin’s multidisciplinary education across environmental science, biomaterials, and biomedical sciences equips him with a unique ability to integrate principles from different scientific domains, making him exceptionally well-prepared for advanced research and innovation in the

field.

Professional Experience📝

Minzhao Lin has developed a strong professional foundation through a blend of academic research, project management, and teaching. Currently serving as a Lecturer at Dezhou College, he is actively involved in mentoring students and contributing to the academic community. During his Ph.D. at Sun Yat-sen University (2020–2024), he played a key administrative role in managing national research projects, including the National Natural Science Foundation of China (NSFC) and the Guangzhou Municipal Key R&D Project. He coordinated proposal submissions, managed financial accounts and procurement, ensured lab safety, and facilitated internal and external collaborations. His leadership led to successful applications for two national key grants and the completion of major project deliverables. Lin’s work spans from preclinical research to translational applications, where he contributed to drug formulation, nanocarrier development, and in vivo efficacy testing. His experience demonstrates not only research expertise but also strategic oversight, teamwork, and organizational skills essential for leading scientific initiatives.

Research Interest🔎

Minzhao Lin’s research interests lie at the intersection of nanomedicine, biomedical engineering, and cancer immunotherapy, with a strong emphasis on translational applications. His primary focus is on ultrasound-based drug delivery systems and the development of smart nanocarriers that respond to biological or external stimuli for targeted therapy. He is particularly interested in using sonogenetics and ultrasound-responsive nanomaterials to enhance the precision and penetration of therapeutic agents, especially in challenging tumor environments. Lin’s work also explores reprogramming the tumor microenvironment to overcome immunosuppression and resistance, thereby improving the efficacy of cancer immunotherapy. His interdisciplinary research integrates principles from materials science, molecular biology, and immunoengineering, aiming to design novel therapeutic platforms that can be effectively translated from bench to bedside. By combining targeted delivery strategies with immune modulation, Lin aspires to create innovative solutions for complex diseases such as triple-negative breast cancer and glioma, ultimately advancing personalized and non-invasive treatment modalitie

Award and Honor🏆

Minzhao Lin has been consistently recognized for his academic excellence and research potential through multiple prestigious awards and honors. During his undergraduate studies at South China Agricultural University, he was a three-time recipient of the National Inspirational Scholarship, an honor bestowed upon the top 5% of students for outstanding academic performance and dedication. This early recognition set the tone for his continued success in higher education. As a Ph.D. candidate at Sun Yat-sen University, he was awarded the Ph.D. Scholarship in 2023, placing him among the top 15% of doctoral students in the program. These accolades highlight his unwavering commitment to scientific inquiry and innovation. In addition to academic awards, Lin has gained recognition in the scientific community through his oral presentation at ChinaNanomedicine 2023, where he presented novel findings on tumor-targeting strategies in breast cancer. His consistent achievements underscore his emerging status as a promising and impactful young researcher.

Research Skill🔬

Minzhao Lin possesses a diverse and advanced set of research skills that span molecular biology, nanomedicine, and biomedical engineering. He is proficient in a wide range of cellular and molecular biology techniques, including flow cytometry, confocal microscopy, western blotting, qPCR, and immunohistochemistry. His expertise extends to animal experimentation and in vivo modeling, where he has successfully established tumor models such as breast cancer, hepatocellular carcinoma, and lung metastasis, and performed techniques like tail vein injections, oral gavage, and in vivo imaging. Lin is highly skilled in the design and synthesis of nanocarriers, including polymeric and lipid-based systems, for targeted drug delivery. Additionally, he is experienced in instrumental techniques like HPLC, GPC, DLS, TEM, SEM, and NMR, which are essential for material characterization. His data analysis proficiency includes software such as GraphPad Prism, R, Origin, and ChemDraw. These capabilities enable him to conduct multidisciplinary, high-impact research with precision and innovation.

Conclusion💡

Minzhao Lin is a highly promising early-career researcher whose contributions to nanomedicine and cancer immunotherapy are both innovative and impactful. His diverse skill set, high-impact publications, and multidisciplinary work on ultrasound-responsive therapeutics mark him as a strong candidate for the Best Researcher Award.

Publications Top Noted✍

  • Title: Dual-mode, regenerated DNA motor for simultaneous detection of viral gene fragments and diagnosis of infectious disease
    Authors: Wei Li, Shuaijing Wang, Minzhao Lin, Xueying Chen, Jiayue Li, Wanling Cui, Rui Wang
    Year: 2025
    Citation: Biosensors and Bioelectronics, 2025-04 | DOI: 10.1016/j.bios.2025.117186

  • Title: Overcoming chemoresistance in acute myeloid leukemia via co-delivery of siGLUT1 and hydroxycamptothecin using hyaluronic acid-conjugated nanocarriers
    Authors: Min-Zhao Lin, Min Li, Hongyan Zhang, Wei-Xiong Li, Zenglin Li, Ling-Zhi Wang, Chao Chen, Xiao-Lan Li, Hong-Jie Fan, Gang-Biao Jiang
    Year: 2025
    Citation: International Journal of Biological Macromolecules, 2025-03 | DOI: 10.1016/j.ijbiomac.2025.142492

  • Title: Track-regenerated DNA motor based on magnetic separation for sensitive and sustainable detection of viral RNA and acetamiprid
    Authors: Wei Li, Shuaijing Wang, Jiayue Li, Manman Duan, Shang Sun, Guanghao Yang, Minzhao Lin
    Year: 2025
    Citation: Microchemical Journal, 2025-03 | DOI: 10.1016/j.microc.2025.113297

  • Title: RCA-Supported Multipedal DNA Walker Integrated with TSDR for Simultaneous Detection of Single Nucleotide Polymorphisms in Circulating Tumor DNA
    Authors: Wei Li, Jiayue Li, Minzhao Lin, Kai Liu, Xiaoting Liu, Yi Zhou, Rui Wang
    Year: 2025
    Citation: Analytical Chemistry, 2025-03-25 | DOI: 10.1021/acs.analchem.5c00557

  • Title: Core–Satellite Nanoassembly Overcomes Spatial Heterogeneity of Dendric Cell Distribution in Pancreatic Tumors for Effective Chemoimmunotherapy
    Authors: Gengjia Chen, Bo Li, Tan Li, Minzhao Lin, Huihai Zhong, Xiaoxue Xie, Qiaoyun Zhang, Qi Chen, Xiaochun Meng, Zecong Xiao
    Year: 2025
    Citation: ACS Nano, 2025-02-04 | DOI: 10.1021/acsnano.4c15444

  • Title: Light-inducible nanodrug-mediated photodynamic and anti-apoptotic synergy for enhanced immunotherapy in triple-negative breast cancer
    Authors: Jing Huang, Xingliang Liu, Minzhao Lin, Zecong Xiao, Xintao Shuai
    Year: 2024
    Citation: Biomaterials Science, 2024 | DOI: 10.1039/d4bm00083h

  • Title: γ-Glutamyl transpeptidase-activable nanoprobe crosses the blood-brain barrier for immuno-sonodynamic therapy of glioma
    Authors: Bo Li, Gengjia Chen, Huihai Zhong, Tan Li, Minzhao Lin, Huiye Wei, Qiaoyun Zhang, Qi Chen, Jinsheng Huang, Xintao Shuai
    Year: 2024
    Citation: Nature Communications, 2024-11-29 | DOI: 10.1038/s41467-024-54382-z

  • Title: Ultrasound-irradiated bindable microbomb opens the blood-brain barrier to enhance glioma therapy
    Authors: Bo Li, Huihai Zhong, Huiye Wei, Gengjia Chen, Minzhao Lin, Sicong Huang, Qiaoyun Zhang, Chengfen Xing, Tan Li, Jinsheng Huang
    Year: 2024
    Citation: Nano Today, 2024-06 | DOI: 10.1016/j.nantod.2024.102312

  • Title: Metal-organic framework nanoparticles hitchhiking on T cells for protein delivery to boost anticancer immunotherapy
    Authors: Jing Huang, Zecong Xiao, Minzhao Lin, Huihai Zhong, Xintao Shuai
    Year: 2024
    Citation: Nano Today, 2024-02 | DOI: 10.1016/j.nantod.2023.102102

  • Title: Twins‐like nanodrugs synchronously transport in blood and coalesce inside tumors for sensitive ultrasound imaging and triggerable penetrative drug delivery
    Authors: Yujun Cai, Gengjia Chen, Minzhao Lin, Bo Li, Huihai Zhong, Tan Li, Zecong Xiao, Yong Wang, Xintao Shuai
    Year: 2024
    Citation: Aggregate, 2024-01-04 | DOI: 10.1002/agt2.476

  • Title: Nanodrug regulates ROS homeostasis via enhancing fatty acid oxidation and inhibiting autophagy to overcome tumor drug resistance
    Authors: HaiYang Wang, Minzhao Lin, Gengjia Chen, Zecong Xiao, Xintao Shuai
    Year: 2023
    Citation: Biomaterials Science, 2023 | DOI: 10.1039/d3bm01139a

  • Title: Anchoring Microbubbles on Cerebrovascular Endothelium as a New Strategy Enabling Low‐Energy Ultrasound‐Assisted Delivery of Varisized Agents Across Blood‐Brain Barrier
    Authors: Bo Li, Yuejun Lin, Gengjia Chen, Mingyue Cai, Huihai Zhong, Zecong Xiao, Minzhao Lin, Tan Li, Yujun Cai, Xintao Shuai
    Year: 2023
    Citation: Advanced Science, 2023-11 | DOI: 10.1002/advs.202302134

 

Minzhao Lin | Biomedical Engineering | Best Researcher Award